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Publications

Peer reviewed publications

2023 Fusion-negative rhabdomyosarcoma 3D organoids to predict effective drug combinations: A proof-of-concept on cell death inducers, Savary et al.,

Model: Rabhdomyosarcoma (pediatric soft-tissue sarcoma) Journal: Nature Cell Reports Medicine

2023 Spatially segregated defects and IGF1-responsiveness of hilar and peripheral biliary organoids from a model of Alagille, Iqbal et al.,

Model: Biliary Organoids Journal: Liver International

2023 A New Approach to Generate Gastruloids to Develop Anterior Neural Tissues, Girgin et al.,

Model: Gastruloids Journal: Bio-protocol

2023 Cutting-edge advances in modeling the blood–brain barrier and tools for its reversible permeabilization for enhanced drug delivery into the brain., Sharma et al.

Model: Blood-brain barrier Journal: Cell & Bioscience

2023 Generating human blastoids modeling blastocyst-stage embryos and implantation., Khoei et al.

Model: Gastruloids Journal: Nature

2022 Rectal organoid-guided CFTR modulator therapy restores lung function in a CF patient with the rare 1677delTA/R334W genotype., Mitropoulou et al.

Model: Intestinal organoids Journal: European Respiratory Journal

2022 Stem cell-derived synthetic embryos self-assemble by exploiting cadherin codes and cortical tension., Bao et al.

Model: Gastruloids Journal: Nature

2022 OrBITS: label-free and time-lapse monitoring of patient derived organoids for advanced drug screening., Deben et al.

Model: Multiple Journal: Cellular Oncology

2022 High Throughput Blood-brain Barrier Organoid Generation and Assessment of Receptor-Mediated Antibody Transcytosis., Kassianidou et al.

Model: Blood-brain barrier Journal: bio-protocol

2022 An automated do-it-yourself system for dynamic stem cell and organoid culture in standard multi-well plates., Tischler et al.

Model: Gastruloids Journal: Cell reports Methods

2022 Cell-state transitions and collective cell movement generate an endoderm-like region in gastruloids., Hashmi et al.

Model: Gastruloids Journal: eLife

2022 Microarrayed human bone marrow organoids for modelling blood stem cell dynamics., Giger et al.

Model:  Bone marrow organoids    Journal: APL Bioengineering

2021 Protocol for automated production of human stem cell derived liver spheres., Mesequer-Ripolles et al.

Model: iPSC-derived hepatic organoids. Journal: STAR Protocols

2021 Investigating receptor-mediated antibody transcytosis using Blood-Brain Barrier organoid arrays., Simonneau et al.

Model: Blood-brain barrier    Journal: Fluids and barriers of the CNS

2021 Bioengineered embryoids mimic post-implantation development in vitro., Girgin et al.

Model: Gastruloids    Journal: Nature Communications

2021 Diagnostic tools and CFTR functional assays in cystic fibrosis: utility and availability in Switzerland. Fernandez-Elviro et al.

Model: Intestinal organoids    Journal: Swiss Medical Weekly

2021 Gastruloids generated without exogenous Wnt activation develop anterior neural tissues. Girgin et al.

Model: Gastruloids    Journal: Stem Cell Reports

2020 Inducible Stem-Cell-Derived Embryos Capture Mouse Morphogenetic Events In Vitro, Amadei et al.,

Model: Gastruloids Journal: Developmental Cell

2020 High-throughput automated organoid culture via stem-cell aggregation in microcavity arrays., Brandenberg et al.

Model: Gastrointestinal organoids, human colorectal cancer tumoroids    Journal: Nature Biomedical Engineering

2020 Hydrogel-based milliwell arrays for standardized and scalable retinal organoid cultures., Decembrini et al.

Model: Retinal organoids    Journal: Scientific Reports

2020 Homeostatic mini-intestines through scaffold-guided organoid morphogenesis., Nikolaev et al.

Model: Perfusable gastrointestinal organoids    Journal: Nature

2020 Development of a cost-effective automated platform to produce human liver spheroids for basic and applied research., Lucendo-Villarin et al.

Model: iPSC-derived hepatic organoids    Journal: Biofabrication

2019 Pharmacological Induction of a Progenitor State for the Efficient Expansion of Primary Human Hepatocytes., Unzu et al.

Model:  Liver progenitor spheroids   Journal: Hepatology

Publications

Pre-prints

2023 Marangoni-like tissue flows enhance symmetry breaking of embryonic organoids, Gsell et al.

Model: Gastruloids Journal: bioRxiv

2021 Probing the killing potency of tumor-infiltrating lymphocytes on microarrayed autologous tumoroids., Dutta et al.

Model: Human colorectal cancer tumoroids, T cell killing assay    Journal: BioRxiv

Posters

Unveiling Drug Responses in Liver Spheroids: Multiplexing 3D Cell-Based Assays and Imaging in a Microwell Platform

In collaboration with Tecan and Promega. As presented at EuroTox, Ljubljana, 2023.

A novel approach for label-free drug efficacy analyses of pancreatic cancer organoids using high-content imaging

In collaboration with Molecular Devices. As presented at MPS summit, Berlin, 2023.

A microwell platform to standardize human rectal organoid cultures for high-content imaging and phenotypic analyses

In collaboration with Molecular Devices. As presented at ELRIG Drug Discovery, London, 2022.

High-content imaging and morphology analyses on standardized human rectal organoid arrays

In collaboration with Molecular Devices. As presented at SLAS Europe, Dublin 2022.

Towards high-throughput modelling of inflammatory bowel disease using human intestinal organoids

In collaboration with Molecular Devices. As presented at ISSCR, San Francisco 2022.

Assessing combination therapies in human pancreatic cancer organoids using a standardized screening workflow

As presented at ISSCR, San Francisco 2022

An automated standardized screening workflow for assessing combination therapies in human pancreatic cancer organoids

As presented at ELRIG Drug Discovery, Liverpool 2021.

Comparison of automated high-content image-based phenotypic screening models for drug discovery: from 2D cultures to 3D spheroids and organoids

As presented at Workshop Organoids in Cancer Research, Lausanne 2021

Product Description

Gri3D® product data sheet

General Protocols with Gri3D®

Organoid array on Gri3D®
Spheroid array on Gri3D®

Protocols Gri3D® 96 Wellplate Format

Click on the microwell size of your Gri3D® to download your protocol

100 μm

400 μm

800 μm

200 μm

500 μm

1000 μm

300 μm

600 μm

1600 μm

Protocols Gri3D® 24 Wellplate Format

Click on the microwell size of your Gri3D® to download your protocol

100 μm

400 μm

800 μm

200 μm

500 μm

1000 μm

300 μm

600 μm

1500 μm

3000 μm

Protocol Gri3D® 96 Wellplate Format Sample

Click here to download the Gri3D® 96 Sample protocol

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